1,10-Phenanthroline hydrate
- Product Name
- 1,10-Phenanthroline hydrate
- CAS No.
- 5144-89-8
- Chemical Name
- 1,10-Phenanthroline hydrate
- Synonyms
- 1,10-PHENANTHROLINE MONOHYDRATE;ORTHO-PHENANTHROLINE;Phenanthroline Monohydrate;1,10-PHENANTHROLINE H2O;O-PHENANTHROLINE MONOHYDRATE;1,10-Phenanthroline, ACS, 99%;10-Phenanthroline monohydrate;PHENYLANTHROLINE HYDRATE 1,10-;1,10-PHENANTHROLINE AR;Black bone vine extract
- CBNumber
- CB8290304
- Molecular Formula
- C12H8N2.H2O
- Formula Weight
- 198.22
- MOL File
- 5144-89-8.mol
1,10-Phenanthroline hydrate Property
- Melting point:
- 100-104 °C(lit.)
- Density
- 1.10
- vapor density
- 6.2 (vs air)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- methanol: soluble200MM (Stock solution is stable for months at –20° C.)
- form
- Needle-Like Crystals
- color
- Off-white, may become cream-colored during storage
- Water Solubility
- <0.01 g/100 mL at 21 ºC
- Merck
- 14,7214
- BRN
- 4008096
- Stability:
- Stable. Incompatible with iron, other heavy metals, strong oxidizing agents, strong acids.
- CAS DataBase Reference
- 5144-89-8(CAS DataBase Reference)
- EPA Substance Registry System
- 1,10-Phenanthroline, monohydrate (5144-89-8)
N-Bromosuccinimide Price
- Product number
- 77500
- Product name
- 1,10-Phenanthroline monohydrate
- Purity
- for the spectrophotometric determination of Fe, Pd, V, ≥99.0%
- Packaging
- 5G
- Price
- $61.4
- Updated
- 2024/03/01
- Product number
- 77500
- Product name
- 1,10-Phenanthroline monohydrate
- Purity
- for the spectrophotometric determination of Fe, Pd, V, ≥99.0%
- Packaging
- 25g
- Price
- $242
- Updated
- 2024/03/01
- Product number
- 320056
- Product name
- 1,10-Phenanthroline monohydrate
- Purity
- ACS reagent, 99%
- Packaging
- 5g
- Price
- $70.8
- Updated
- 2024/03/01
- Product number
- 320056
- Product name
- 1,10-Phenanthroline monohydrate
- Purity
- ACS reagent, 99%
- Packaging
- 25g
- Price
- $209
- Updated
- 2024/03/01
- Product number
- 1.07225
- Product name
- 1,10-Phenanthroline monohydrate
- Purity
- GR ACS
- Packaging
- 10g
- Price
- $242
- Updated
- 2024/03/01
1,10-Phenanthroline hydrate Chemical Properties,Usage,Production
Chemical Properties
white crystals or powder
Uses
1,10-Phenanthroline monohydrate is useful to study the DNA-protein interactions due to its nuclease activity. It is used as a redox indicator and reagent for spectrophotometric assay of silver. It acts as a chelating ligand for the determination of Fe, Pd and V. It also acts as a matrix metalloproteinase inhibitor. It is a photometric reagent for iron, which forms a red chelate with ferrous (iron II) ion.
Uses
When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions.
1,10-Phenanthroline monohydrate is an aromatic nitrogen heterocycle that may be used as a chelating agent in the preparation of metal-chelate complexes.
General Description
White crystalline powder or solid. Slight odor.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
1,10-Phenanthroline hydrate is incompatible with strong oxidizers. 1,10-Phenanthroline hydrate is also incompatible with strong acids. 1,10-Phenanthroline hydrate forms complex compounds with ferrous ions. .
Fire Hazard
Flash point data for 1,10-Phenanthroline hydrate are not available. 1,10-Phenanthroline hydrate is probably combustible.
Biochem/physiol Actions
Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM.
Purification Methods
Crystallise its picrate (m 191o) from EtOH; then the free base is liberated with aqueous alkali, dried at 78o/8mm over P2O5 and crystallised from pet ether (b 80-100o). [Cumper et al. J Chem Soc 1188 1962.] It can be purified by zone melting. It has also been crystallised from hexane, *benzene/pet ether (b 40-60o) or sodium-dried *benzene, dried and stored over H2SO4. The monohydrate is obtained by crystallisation from aqueous EtOH or ethyl acetate. It has been crystallised from H2O (300 parts) to give the monohydrate m 102-103o which sublimes at 10-3mm [Fielding & LeFevre J Chem Soc 1811 1951.] The anhydrous compound has m 118o (after drying at high vacuum at 80o) and is also obtained by recrystallisation from pet ether or *C6H6 (70 parts) and drying at 78o/8mm. [UV: Badger et al. J Chem Soc 3199 1951.] IthasapKainH2Oof 4.857 (25o) or 5.02 (20o) and 4.27 in 50% aqueous EtOH (20o). [Albert et al. J Chem Soc 2240 1948]. [Beilstein 23 H 227, 23 II 235, 23/8 V 419.]
1,10-Phenanthroline hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
1,10-Phenanthroline hydrate Suppliers
- Tel
- +1-510-219-6317
- Fax
- +1-650-486-1361
- sales@hbcchem.com
- Country
- United States
- ProdList
- 10658
- Advantage
- 60
- Tel
- +1-833-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 57511
- Advantage
- 58
- Tel
- +1-781-999-5354
- support@targetmol.com
- Country
- United States
- ProdList
- 19973
- Advantage
- 58
View Lastest Price from 1,10-Phenanthroline hydrate manufacturers
- Product
- 1,10-Phenanthroline monohydrate 5144-89-8
- Price
- US $100.00-95.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 6000 per month
- Release date
- 2023-01-03
- Product
- 1,10-Phenanthroline hydrate 5144-89-8
- Price
- US $8.00-0.80/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09
- Product
- 1,10-phenanthrollne monohydrate 5144-89-8
- Price
- US $22.00-161.00/g
- Min. Order
- 100g
- Purity
- 0.98
- Supply Ability
- 100kg
- Release date
- 2023-10-18